Generally, no. A sweeping requirement by an employer that all employees must disclose their prescription medications would likely violate the Americans With Disabilities Act (ADA). However, an employer may make employees disclose their medications where there is a safety or business reason for doing so. A safety reason might be where an employee operates machinery. 

The answer to these type of questions is not often clear-cut and much will depend on the employee's job duties and work environment.  But a requirement that all employees no matter what they do must disclose their medications is going to raise some issues under the ADA.

Lexington, Kentucky disability discrimination lawyer Robert Abell represents individuals and employees who have suffered discrimination on account of a disability; contact him at 859-254-7076.